Python · R · Galaxy

Software

Tools, pipelines and tutorials I develop or maintain. Most are written in Python and R and are openly available.

Pipeline

HmtG-PacBio-Pipeline

Machine-learning workflow (variational autoencoder) that sorts PacBio HiFi mitochondrial reads into parasite haplotypes and species, including mixed infections.

  • Python
  • PacBio HiFi
  • VAE
Documentation →
Workflow

PAL2NAL

Codon-based alignment of coding sequences using PAL2NAL.

  • Alignment
  • Codons
GitHub →
Community project

Galaxy · BRC Analytics

BRC Analytics brings reference genomic data for pathogens, hosts and vectors together with Galaxy workflows that run on shared infrastructure. I develop reproducible pathogen-genomics workflows for the project.

  • Galaxy
  • Workflows
  • Open science
brc-analytics.org →

Tutorials and workshops

Tutorial

Macro-evolutionary Pangenomics

A Plasmodium case study of pangenome analysis across the monkey-parasite clade.

  • Pangenomics
  • Plasmodium
GitHub →
Tutorial

Phylogenetic substitution models

Maximum-likelihood model comparison in orthopoxviruses.

  • Maximum likelihood
  • Phylogenetics
GitHub →
Workshop

Hybrid genome assembly

Hybrid assembly of Leptospira interrogans serovar Copenhageni.

  • Assembly
  • Long + short reads
GitHub →